Open Access Open Access  Restricted Access Subscription Access

3-(NITROMETHYL)-3,4-DIHYDROQUINOXALIN-2(1H)-ONES: SYNTHESIS AND STRUCTURE

Василий В. Пелипко, Сергей В. Макаренко, Валентина М. Берестовицкая, Руслан И. Байчурин
Cover Image

Abstract


Reactions of ethyl 3-nitroacrylate with о-phenylenediamine and its substituted derivatives were used for the synthesis of 3-(nitromethyl)-3,4-dihydroquinoxalin-2(1H)-ones, followed by structural characterization. These compounds were found to undergo elimination of nitromethane, leading to quinoxalin-2(1H)-ones.

Authors: Vasilii V. Pelipko, Sergey V. Makarenko, Valentina M. Berestovitskaya*, Ruslan I. Baichurin


Keywords


1,2-diaminobenzene; ethyl 3-nitroacrylate; 3-(nitromethyl)-3,4-dihydroquinoxalin-2(1H)-one; quinoxalin-2(1Н)-one; aza-Michael reaction

Full Text: PDF (Russian) Supplementary File(s): Supporting information (5MB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv