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SYNTHESIS OF 3-ARYLAMINO-6-PHENYL[1,2,4]TRIAZOLO[3,4-b][1,3,4]THIADIAZINE DERIVATIVES AS POTENTIAL BIOACTIVE MOLECULES

Suyog Marathe, Anil V. Karnik
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Abstract


4-Amino-3-arylamino-5-mercapto-1,2,4-triazoles have been used as synthons for the synthesis of fused ring system of 3-arylamino-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines. The reaction in high yield produces compounds with bridgehead nitrogen and two separate hydrazine units in the molecule making them potential candidates for possessing various biological activities.


Keywords


4-amino-3-arylamino-5-mercapto-1,2,4-triazoles; 3-arylamino-6-phenyl[1,2,4]triazolo[3,4-b][1,3,4]thiadiazines; (2-arylamino-1,3,4-thiadiazol-5-yl)(benzyl)sulfones

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