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INTERACTION OF 1,1,3,3-TETRAMETHYLGUANIDINE WITH 3-ACYL-4Н-CHROMENES

Виталий А. Осянин, Юлия В. Попова, Дмитрий В. Осипов, Юрий Н. Климочкин
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Abstract


A series of substituted 2-(3-oxoprop-1-en-1-yl)guanidines was obtained via the interaction of 1,1,3,3-tetramethylguanidine with fused 4Н-pyrans, containing a carbonyl group in the β-position to the oxygen atom. The proposed reaction mechanism includes a conjugate 1,4-addition with subsequent opening of the dihydropyran ring.

Authors: Vitaly A. Osyanin*, Yulia V. Popova, Dmitry V. Osipov, Yuri N. Klimochkin


Keywords


1,1,3,3-tetramethylguanidine; electron-deficient 4Н-chromenes; push-pull 2-aza-1,3-dienes; Michael reaction

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