EFFICIENT SYNTHESIS OF BENZIMIDAZOLES CONTAINING 1,2,4-TRIAZOL-3-ONE NUCLEUS USING MICROWAVE IRRADIATION

Emre Menteşe, Bahittin Kahveci
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Abstract


A series of new compounds containing both benzimidazole and 1,2,4-triazol-3-one rings was synthesized by microwave irradiation of mixtures containing 5-(alkyl/phenyl)-4-(4-carboxyphenyl)-2,4-dihydro-3H-1,2,4-triazol-3-ones and 1,2-diaminobenzene derivatives. Also, benzimidazole derivatives were synthesized by the reaction of ethyl 2-(ethoxy(alkyl/phenyl)methylene)hydrazine-1-carboxylates with 2-aminobenzimidazole. A rapid and efficient combination of 1,2,4-triazol-3-one and benzimidazole ring systems was achieved for the first time in this study.


Keywords


2-aminobenzimidazole; benzimidazole; hydrazone; 1,2,4-triazol-3-one; microwave synthesis

Supplementary File(s): None


 

 

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