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SYNTHESIS OF HIGHLY SUBSTITUTED 2-PYRIDONES

Maria A. Vodolazhenko, Nikolay Yu. Gorobets
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Abstract


Modern methods for the synthesis of highly substituted 2-pyridones are overviewed making a special emphasis on the interaction between C1-electrophiles, α-carbonyl CH-acids, and active methylene nitriles under microwave irradiation.


Keywords


2-pyridone; microwave-assisted synthesis; Hantzsch reaction; N,N'-dimethylformamide dimethyl acetal

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