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ACID-CATALYZED REACTION OF PHENOLS WITH N-(4,4-DIETHOXYBUTYL)SULFONAMIDES – A NEW METHOD FOR THE SYNTHESIS OF 2-ARYL-1-SULFONYLPYRROLIDINES

Андрей В. Смолобочкин, Альмир С. Газизов, Екатерина А. Аникина, Александр Р. Бурилов, Михаил А. Пудовик
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Abstract


We have developed a new method for the synthesis of 2-aryl-1-sulfonylpyrrolidines on the basis of reactions between various phenols and N-(4,4-diethoxybutyl)sulfonamides in the presence of trifluoroacetic acid. The structures of the obtained products were confirmed by 1Н and 13С NMR spectroscopy, IR spectroscopy, and X-ray structural analysis.

Authors: Andrey V. Smolobochkin, Almir S. Gazizov*, Ekaterina A. Anikina,
Alexander R. Burilov, Michael A. Pudovik

 

 


Keywords


1-сульфонил-2-арилпирролидины; N-(4,4-диэтоксибутил)сульфонамиды; фенолы; 2-этоксипирролидины; сульфохлориды

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