A NEW ROUTE TO HIGHLY SUBSTITUTED THIENO[2,3-<i>b</i>]PYRIDINES <i>VIA</i> CASCADE HETEROCYCLIZATION OF 2-ACYL-1,1,3,3-TETRACYANOPROPENIDE SALTS

Authors

  • Arthur Grigor'ev Chuvash State University named after I. N. Ulyanov, 15 Moskovsky Ave., Cheboksary 428015
  • Sergey Karpov Chuvash State University named after I. N. Ulyanov, 15 Moskovsky Ave., Cheboksary 428015
  • Yakov Kayukov Chuvash State University named after I. N. Ulyanov, 15 Moskovsky Ave., Cheboksary 428015
  • Oleg Nasakin Chuvash State University named after I. N. Ulyanov, 15 Moskovsky Ave., Cheboksary 428015
  • Iuliia Gracheva Nizhni Novgorod State University, 23 Gagarina Ave., Nizhni Novgorod 603950
  • Victor Tafeenko Lomonosov Moscow State University, 1-3 Leninskie Gory, Moscow 119991

DOI:

https://doi.org/10.1007/3554

Keywords:

organic nitriles, tetracyanopropenides, thieno[2, 3-b]pyridines, cyano group

Abstract

2-Acyl-1,1,3,3-tetracyanopropenides undergo cascade heterocyclization under the action of mercaptoacetic esters, leading to the formation of new 3,6-diamino-4-aroyl-5-cyanothieno[2,3-b]pyridine-2-carboxylates. The fast and convenient synthetic way to highly substituted thieno[2,3-b]pyridine scaffold is described.

Author Biography

Sergey Karpov, Chuvash State University named after I. N. Ulyanov, 15 Moskovsky Ave., Cheboksary 428015

Доцент кафедры органической и фармацевтической химии Химико-фармацевтического факультета ФГБОУ ВО "ЧГУ им. И.Н. Ульянова"

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Published

2017-03-09

Issue

Vol. 53 No. 2 (2017)

Section

Original Papers