CYCLOCONDENSATION OF 3(5)-AMINOPYRAZOLES WITH ARYLGLYOXALS AND CYCLOHEXANE-1,3-DIONES
DOI:
https://doi.org/10.1007/359Keywords:
3(5)-aminopyrazoles, arylglyoxals, cyclohexane-1, 3-diones, hexahydropyrazolo[1, 5-a]quinazolinecarboxamides, tetrahydropyrazolo[3, 4-b]quinolinones, acylation, alkylation, oxidation, three-component cyclizationAbstract
Partly hydrogenated 4-aroyl-substituted pyrazolo[3,4-b]quinolin-5-ones and 5-aroyl-substituted pyrazolo[1,5-a]quinazolin-6-ones were obtained by three-component cyclocondensation of substituted 3(5)‑aminopyrazoles with the arylglyoxal hydrates and dimedone, 1,3-cyclohexanedione, or 4,4-dimethylcyclohexanedione in an alcohol medium. The chemical transformations of pyrazolo[3,4-b]quinolin-5-ones in reactions with hydrazine hydrate and also upon alkylation, acylation, and oxidation were studied.
Authors: O. N. Petrova, L. L. Zamigailo, M. G. Shirobokova, S. V. Shishkina, O. V. Shishkin, V. I. Musatov, and V. V. Lipson
English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (7), pp 955-967
