2-(AZOLYL)ANILINES: METHODS OF SYNTHESIS, CYCLOCONDENSATIONS, AND BIOLOGICAL PROPERTIES

Oleksii M. Antypenko; Sergiy V. Kholodnyak; Konstantin P. Schabelnyk; Lyudmyla M. Antypenko; Sergiy Ivanovich Kovalenko

doi:10.1007/3646

2-(AZOLYL)ANILINES: METHODS OF SYNTHESIS, CYCLOCONDENSATIONS, AND BIOLOGICAL PROPERTIES

Oleksii M. Antypenko, Sergiy V. Kholodnyak, Konstantin P. Schabelnyk, Lyudmyla M. Antypenko, Sergiy Ivanovich Kovalenko

Abstract

This review offers summary and analysis of the data on the synthesis of 2-(azolyl)anilines published from 1942 to 2016. It is shown, that they act as effective 1,5-nucleophiles in cyclocondensation reactions. Besides, biological activity data on 2-(azolyl)anilines and their derivatives are reported.

Keywords

azoles; 2-(azolyl)anilines; 1,5-binucleophiles; biological activity; cyclocondensation; synthesis

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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