2-(AZOLYL)ANILINES: METHODS OF SYNTHESIS, CYCLOCONDENSATIONS, AND BIOLOGICAL PROPERTIES

Authors

  • Oleksii M. Antypenko Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035
  • Sergiy V. Kholodnyak Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035
  • Konstantin P. Schabelnyk Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035
  • Lyudmyla M. Antypenko Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035
  • Sergiy Ivanovich Kovalenko Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

DOI:

https://doi.org/10.1007/3646

Keywords:

azoles, 2-(azolyl)anilines, 1, 5-binucleophiles, biological activity, cyclocondensation, synthesis

Abstract

This review offers summary and analysis of the data on the synthesis of 2-(azolyl)anilines published from 1942 to 2016. It is shown, that they act as effective 1,5-nucleophiles in cyclocondensation reactions. Besides, biological activity data on 2-(azolyl)anilines and their derivatives are reported.

Author Biographies

Oleksii M. Antypenko, Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

Oleksii Mykolayovych Antypenko

Sergiy V. Kholodnyak, Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

Sergiy Valerievich Kholodnyak

Konstantin P. Schabelnyk, Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

Konstantin Petrovich Schabelnyk

Lyudmyla M. Antypenko, Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

Lyudmyla MykolaivnaAntypenko

Sergiy Ivanovich Kovalenko, Zaporizhzhia State Medical University, 26, Mayakovsky Ave., Zaporizhzhia 69035

Sergiy Ivanovich Kovalenko

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Published

2017-04-13

Issue

Vol. 53 No. 3 (2017): Privileged heterocyclic scaffolds in chemical biology and drug discovery: synthesis and bioactivity

Section

Review Articles