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THREE-COMPONENT REACTION OF KETALS, ISONITRILES, AND TRIMETHYLSILYL AZIDE

Никита Е. Голанцов, Хунг М. Нгуен, Алексей В. Варламов, Александр В. Аксенов, Леонид Г. Воскресенский
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Abstract


It was demonstrated that a ZnCl2-catalyzed three-component reaction of ketals, isonitriles, and trimethylsilyl azide led to 1,5-disubstituted tetrazoles in moderate to high yields.

 

Authors: Nikita E. Golantsov, Hung M. Nguyen, Aleksey V. Varlamov, Aleksander V. Aksenov, Leonid G. Voskressensky

 


Keywords


isonitrile; ketal; tetrazole; trimethylsilyl azide; Passerini reaction

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