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SYNTHESIS OF 4-(4-OXO-1,3-THIAZOLIDIN-2-YLIDENE)PYRROLIDINE-2,3,5-TRIONES

Константин Л. Обыденнов, Алексей Н. Галущинский, Мария Ф. Костерина, Татьяна В. Глухарева, Юрий Ю. Моржерин
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Abstract


It was shown that 2-(1,3-thiazolidin-2-ylidene)acetamides can be used as 2-enamides in cyclocondensation reactions with oxalyl chloride, leading to the formation of new heterocyclic assemblies – 4-(4-oxo-1,3-thiazolidin-2-ylidene)pyrrolidine-2,3,5-triones in 50–88% yields.

Authors: Konstantin L. Obydennov, Aleksei N. Galushchinsky,
Marya F. Kosterina, Tatiana V. Glukhareva, Yuri Yu. Morzherin

 


Keywords


oxalyl chloride; pyrrolidine-2,3,5-trione; thiazolidin-4-one; cyclocondensation; exocyclic double bond; heterocyclic assemblies

Full Text: PDF (Russian) Supplementary File(s): Supporting information (8MB)


 

 

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