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SYNTHESIS OF TETRAZOLE AND ITS DERIVATIVES BY HETEROCYCLIZATION REACTION INVOLVING PRIMARY AMINES, ORTHOESTERS, AND AZIDES

Юрий В. Григорьев, Сергей В. Войтехович, Владимир П. Каравай, Олег А. Ивашкевич
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Abstract


This review provides comprehensive analysis of literature data on the heterocyclization reaction of primary amines, orthoesters, and azides, which can be used for the preparation of tetrazole, its 1-mono- and 1,5-disubstituted derivatives.

Authors: Yurii V. Grigoriev, Sergei V. Voitekhovich, Vladimir P. Karavai, Oleg A. Ivashkevich*

 


Keywords


orthoesters; primary amines; tetrazole; heterocyclization; multicomponent reaction

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