ACYLATION OF AMINES AND PYRAZOLE WITH [2-ISOPROPYL-4-(<i>o</i>-METHOXYPHENYL)-TETRAHYDROPYRAN-4-YL]ACETYL CHLORIDE

Authors

  • Н. С. Арутюнян The Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, A. L. Mnjoyan Institute of Fine Organic Chemistry
  • Н. З. Акопян The Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, A. L. Mnjoyan Institute of Fine Organic Chemistry
  • Л. А. Акопян The Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, A. L. Mnjoyan Institute of Fine Organic Chemistry
  • Г. А. Геворгян The Scientific Technological Center of Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia, A. L. Mnjoyan Institute of Fine Organic Chemistry
  • Г. А. Паносян Molecular Structure Research Center of the Scientific Technological Center for Organic and Pharmaceutical Chemistry, National Academy of Sciences of Armenia

DOI:

https://doi.org/10.1007/404

Keywords:

[2-isopropyl-4-(o-methoxyphenyl)tetrahydropyran-4-yl]acetic acid, N-substituted amides, acylation, hydrolysis

Abstract

[2-Isopropyl-4-(o-methoxyphenyl)tetrahydropyran-4-yl]acetic acid has been obtained by the hydrolysis of previously synthesized [2-isopropyl-4-(o-methoxyphenyl)tetrahydropyran-4-yl]acetonitrile. The acyl chloride prepared from this acid gave new amides and 1-acylpyrazole upon interaction with various amines and with pyrazole.

Authors: N. S. Arutjunyan, N. Z. Hakobyan, L. A. Hakobyan, G. A. Gevorgyan, and G. A. Panosyan

English Translation in Chemistry of Heterocyclic Compounds, 2013, 49 (2), pp 249-252

http://link.springer.com/article/10.1007/s10593-013-1241-1

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Published

2013-03-18

Issue

No. 2 (2013)

Section

Original Papers