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METHYLAMINO- AND DIMETHYLAMINOQUINOLINES

Ольга Валерьевна Дябло, Александр Федорович Пожарский, Елена Анатольевна Носачева
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Abstract


Methods for the synthesis and the properties of methylamino- and  dimethylaminoquinolines, as well as the interactions between their amino groups and the heteroatom of the ring are reviewed. Particular attention is devoted to the recently obtained 4,5-bis(dimethylamino)- quinolines, which are protonated depending on the substituients primarily at the quinoline ring nitrogen atom or at the peridimethylamino groups. In the latter case these compounds can be characterized as proton sponges. A total of 134 literature references are presented.

Keywords


4,5-diaminoquinolines, dimethylaminoquinolines, methylaminoquinolines, protonation direction, proton sponges.

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