1,3-DIPOLAR CYCLOADDITION OF 1-SUBSTITUTED 3,3,3-TRIFLUOROPROPENES TO ETHYL CYANOCARBOXYLATE <i>N</i>-OXIDE

Authors

  • Юрий Н. Маркитанов Institute of Organic Chemistry, National Academy of Sciences of Ukraine
  • Вадим М. Тимошенко Institute of Organic Chemistry, National Academy of Sciences of Ukraine
  • Юрий Г. Шермолович Institute of Organic Chemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/4092

Keywords:

isoxazole, nitrile oxide, sulfamide, sulfone, sulfoximine, cycloaddition, trifluoromethyl group

Abstract

3,3,3-Trifluoropropene derivatives containing a sulfonyl, sulfoximine, or sulfamide substituent at position 1 were used in 1,3-dipolar cycloaddition reaction with ethyl cyanocarboxylate N-oxide generated by thermal decomposition of ethyl oximinochloroacetate, resulting in the formation of isomeric 4(5)-substituted ethyl 5(4)-(trifluoromethyl)-4,5-dihydroisoxazole-3-carboxylates and ethyl 4-(trifluoromethyl) isoxazole-3-carboxylate.

Author Biographies

Вадим М. Тимошенко, Institute of Organic Chemistry, National Academy of Sciences of Ukraine

Вадим Михайлович Тимошенко

Юрий Г. Шермолович, Institute of Organic Chemistry, National Academy of Sciences of Ukraine

Юрий Григорьевич Шермолович

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Published

2018-02-17

Issue

Vol. 54 No. 1 (2018)

Section

Short Communications