

CHEMOSELECTIVE IODINATION OF 6-SUBSTITUTED IMIDAZO[1,2-a]PYRIDINE

Abstract
3- and 8-Iodoimidazo[1,2-a]pyridines were synthesized from imidazo[1,2-a]pyridine under different substitution conditions. The molecular electrostatic potential calculations were performed to investigate the chemoselectivity of the substitution reaction. The molecular structures of the target compounds were characterized by single crystal X-ray diffraction analysis.
Keywords
imidazo[1,2-a]pyridine; heteroaryl iodides; synthesis; X-ray diffraction.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv