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REACTION OF N-(3-OXOALKENYL)CHLOROACETAMIDES WITH SODIUM p-TOLUENESULFINATE – SYNTHESIS OF 3-TOSYLPYRIDIN-2(1Н)-ONES

Дмитрий С. Гончаров, Иван В. Кулаков, Александр С. Фисюк
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Abstract


A series of N-(3-oxoalkenyl)chloroacetamides was prepared by acylation of β-enaminoketones with chloroacetyl chloride. A reaction of these compounds with sodium p-toluenesulfinate in dimethylformamide in the presence of potassium carbonate led to 3-tosylpyridin-2(1H)-ones. The limitations of this reaction were studied.

Authors: Dmitry S. Goncharov, Ivan V. Kulakov, Alexander S. Fisyuk*


Keywords


enaminoketones; N-(3-oxoalkenyl)chloroacetamides; 3-tosylpyridin-2(1H)-ones; intramolecular cyclization

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