NEW METHOD FOR THE SYNTHESIS OF 2-HETARYL-2-(1-R-PYRROLIDIN-2-YLIDENE)ACETONITRILES

Authors

  • Елена А. Кулешова Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601
  • Ольга В. Хиля Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601
  • Юлиан М. Воловенко Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601

DOI:

https://doi.org/10.1007/4189

Keywords:

hetarylacetonitriles, 2-hetaryl-2-(1-R-pyrrolidin-2-ylidene)acetonitriles, pyrrolinium salts, condensation reactions, three-component reaction

Abstract

New method was developed for the synthesis of 2-hetaryl-2-(1-R-pyrrolidin-2-ylidene)acetonitriles by using a three-component condensation of hetarylacetonitrile, phosphorus oxychloride, and 1-R-pyrrolidin-2-one. This method is applicable to the synthesis of β-enaminonitriles containing azoles and six-membered azaheteroaromatic rings at the α-position relative to the nitrile group.

Authors: Olena A. Kuleshova*, Olga V. Khilya, Yulian M. Volovenko

Author Biographies

Елена А. Кулешова, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601

Аспирант (химический факультет)

Ольга В. Хиля, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601

к.х.н., доцент (химический факультет)

Юлиан М. Воловенко, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601

д.х.н., профессор (химический факультет)

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Published

2018-02-16

Issue

Vol. 54 No. 1 (2018)

Section

Short Communications