

SYNTHESIS AND TUBERCULOSTATIC ACTIVITY OF FUNCTIONALIZED PYRAZOLES DERIVED FROM (TRIFLUOROMETHYL)PYRAZOLE CONTAINING A HYDRAZONE GROUP

Abstract
The condensation of 5-(1-hydrazinylideneethyl)-3-(trifluoromethyl)-1H-pyrazole with trimethyl orthoacetate, dimethylformamide
dimethyl acetal, and aryl thioisocyanates resulted in a series of functionalized pyrazoles and their tuberculostatic activity was studied.
dimethyl acetal, and aryl thioisocyanates resulted in a series of functionalized pyrazoles and their tuberculostatic activity was studied.
Keywords
hydrazones, pyrazole, thiosemicarbazides, condensation.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv