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SYNTHESIS AND TUBERCULOSTATIC ACTIVITY OF FUNCTIONALIZED PYRAZOLES DERIVED FROM (TRIFLUOROMETHYL)PYRAZOLE CONTAINING A HYDRAZONE GROUP

Денис Назарович Бажин, Юлия Сергеевна Кудякова, Александра Яновна Оноприенко, Павел Александрович Слепухин, Янина Валерьевна Бургарт, София Сергеевна Борисевич, Сергей Леонидович Хурсан, Виктор Иванович Салоутин
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Abstract


The condensation of 5-(1-hydrazinylideneethyl)-3-(trifluoromethyl)-1H-pyrazole with trimethyl orthoacetate, dimethylformamide
dimethyl acetal, and aryl thioisocyanates resulted in a series of functionalized pyrazoles and their tuberculostatic activity was studied.

Keywords


hydrazones, pyrazole, thiosemicarbazides, condensation.

Full Text: PDF (Russian) Supplementary File(s): Supporting information (845KB)


 

 

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