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A STUDY OF PLANT COUMARINS. 16. SYNTHESIS AND TRANSFORMATIONS OF 7-ALKYNYLCOUMARINS

Алла В. Липеева, Эльвира Э. Шульц
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Abstract


7-Alkynyl-substituted coumarins were synthesized by a Sonogashira reaction of 6-substituted 7-(trifluoromethylsulfonyloxy)coumarins with terminal acetylenes. The reaction of 7-ethynyl-substituted coumarins with azidobenzoic acids in the presence of copper(II) sulfate and sodium ascorbate was used to synthesize the respective 7-[(1-carboxyphenyl)-1H-1,2,3-triazol-4-yl]coumarins.

Authors: Alla V. Lipeeva, Elvira E. Shults*


Keywords


arylalkynes; coumarins; 1,2,3-triazoles; CuААС reaction; Sonogashira reaction

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