SYNTHESIS OF SPIRO[IMIDAZO[2,1- b ][1,3]THIAZOLE- 6,3'-PYRROLIDINE] DERIVATIVES

Леся Н. Салиева; Наталия Ю. Сливка; Дмитрий А. Мельник; Эдуард Б. Русанов; Руслан И. Васькевич; Михаил В. Вовк

doi:10.1007/4332

SYNTHESIS OF SPIRO[IMIDAZO[2,1-b][1,3]THIAZOLE- 6,3'-PYRROLIDINE] DERIVATIVES

Леся Н. Салиева, Наталия Ю. Сливка, Дмитрий А. Мельник, Эдуард Б. Русанов, Руслан И. Васькевич, Михаил В. Вовк

Abstract

6-Arylidene-2,3-dihydroimidazo[2,1-b][1,3]thiazol-5(6Н)-ones reacted with N-alkylazomethine ylides by [2+3] cycloaddition mechanism, resulting in the formation of diastereomeric spiro[imidazo[2,1-b][1,3]thiazole-6,3'-pyrrolidin]-5(6Н)-ones, which were separated by column chromatography.

Keywords

6-arylideneimidazo[2,1-b][1,3]thiazoles, azomethine ylides, spiro[imidazo[2,1-b][1,3]thiazole-6,3'-pyrrolidines], [2+3] cycloaddition.

Full Text: PDF (Russian) Open Access

Supplementary File(s): None

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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