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ECO-COMPATIBLE SYNTHESIS OF NOVEL 3-HYDROXYFLAVONES CATALYZED BY KF-IMPREGNATED MESOPOROUS NATURAL ZEOLITE CLINOPTILOLITE

Hadi Sajjadi-Ghotbabadi, Shahrzad Javanshir, Faramarz Rostami-Charati, Seyyed Zahra Sayyed-Alangi
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Abstract


A series of novel 3-hydroxyflavones were designed and synthesized under efficient and green one-pot three-component aldol condensation/intramolecular cyclization reaction of 1-[6-hydroxy-2-(prop-1-en-2-yl)-1-benzofuran-5-yl]ethanone, substituted benzaldehyde, and hydrogen peroxide in the presence of potassium fluoride /clinoptilolite nanocatalyst in water at room temperature.


Keywords


clinoptilolite; 3-hydroxyflavone; potassium fluoride; nanocatalyst; eco-compatible synthesis

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv