2-(3-ACETYLAMINO-2,2-DIMETHYLCYCLOBUTYL)METHYL-4(3H)-QUINAZOLINONES

Ф. М. Авотиньш, М. В. Петрова, Н. Н. Тонких, А. Я. Страков

Abstract


Beckmann rearrangement of N-[3-(1-hydroxyimino)ethyl-2,2-dimethylcyclobutyl]acetylanthranilic acid, and its 5-bromo and 4-chloro derivatives gives the corresponding N-(3-acetylamino-2,2-dimethylcyclobutyl)acetylanthranilic acids. Treatment of these acylanthranilic acids with formamide gives 2-(3-acetylamino-2,2-dimethylcyclobutyl)methyl-4(3H)-quinazoline and its 6-bromo and 7-chloro derivatives.

Authors: F. M. Avotin'sh, M. V. Petrova, N. N. Tonkikh, and A. Strakov.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (11), pp 1326-1328

http://link.springer.com/article/10.1023/A%3A1017579719809


Keywords


N-[3-(1-hydroxyimino)ethyl-2,2-dimethylcyclobutyl]acetylanthranilic acids; Beckmann rearrangement; 2-(3-acetylamino-2,2-dimethylcyclobutyl)methyl-4(3H)-quinazoline; 6-bromo derivatives of 2-(3-acetylamino-2,2-dimethylcyclobutyl)methyl-4(3H)-quinazoline; 7

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