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ON THE PRINS REACTION OF TERMINAL OLEFINS AND FORMALDEHYDE IN TRIFLUOROACETIC ACID

Hasanain A. A. Almohseni, Matthew A. H. Stent, David M. Hodgson
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Abstract


The Prins reaction of 1-heptene, as a representative terminal alkene, with formaldehyde in trifluoroacetic acid produces 3-butyl-4-(trifluoroacetoxy)tetrahydropyran and/or 3-butyl-4-hydroxytetrahydropyran; it does not provide (as previously reported by Talipov and coworkers) a route to 3-alkyl-2,5-dihydrofurans and 4-alkyl-3-hydroxytetrahydrofurans.

Keywords


formaldehyde; terminal alkenes; tetrahydropyrans; trifluoroacetic acid; Prins reaction

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