ZnO NANOROD-CATALYZED THREE-COMPONENT REACTION OF EUPARIN, ALDEHYDE, AND DIALKYL ACETYLENEDICARBOXYLATE: GREEN SYNTHESIS OF CHROMENE DERIVATIVES

Authors

  • Fatemeh Sheikholeslami-Farahani Department of Chemistry, Firoozkooh Branch, Islamic Azad University, Firoozkooh
  • Hossein Karami Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr
  • Masoomeh Salimifard Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr
  • Saeid Afshari Sharif Abad Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr
  • Ali Akbar Eslami Department of Chemistry, Qaemshahr Branch, Islamic Azad University, Qaemshahr

DOI:

https://doi.org/10.1007/4377

Keywords:

chromen, dialkyl acetylenedicarboxylate, euparin, triphenylphosphine, green synthesis, solvent-free

Abstract

New chromene derivatives, 9H-furo[2,3-f]chromene-7,8-dicarboxylates, have been synthesized in high yields by a three-component reaction of euparin (isolated from Petasites hybridus), an aldehyde, and dialkyl acetylenedicarboxylate in the presence of PPh3 and catalytic amount of ZnO nanorods under solvent-free conditions at room temperature. ZnO nanorods showed a strong effect on improving the yield of the desired products. Chromene derivatives can be easily separated from the reaction mixture in a simple work-up, and the catalyst may be recovered and reused without considerable loss of activity.

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Published

2018-07-26

Issue

Vol. 54 No. 6 (2018)

Section

Original Papers