

NICKEL-CATALYZED MULTICOMPONENT HETEROCYCLIZATION OF 2,4-PENTANEDIONE TO SULFANYLMETHYL-1Н-PYRAZOLES

Abstract
A one-pot synthesis of new sulfanylmethyl-substituted 3,5-dimethyl-1H-pyrazoles with fungicidal activity was based on a nickelcatalyzed four-component condensation of 2,4-pentanedione with formaldehyde, thiols, and hydrazine hydrate.
Keywords
hydrazine hydrate, 2,4-pentanedione, sulfanylmethyl-substituted pyrazoles, thiols, catalysis, fungicidal activity, multicomponent reactions.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv