

REACTIONS OF 2Н(4Н)-CHROMENES WITH DINUCLEOPHILES: ONE-STEP SYNTHESIS OF 2-(1H-(BI)PYRAZOL-3-YL)- AND 2-(1,4(5)-(BENZO)DIAZEPIN-4-YL)PHENOLS

Abstract
Novel derivatives of 2-(1H-(bi)pyrazol-3-yl)phenols and 2-(1,4(5)-(benzo)diazepin-4-yl)phenols were obtained in the reaction of (4-amino-2H-chromen-2-ylidene)malondialdehyde and 4H-chromen-4-imines with 1,2-, 1,3-, and 1,4-dinucleophiles proceeding as a cascade reaction initiated by the Michael reaction.
Keywords
chromenes, dipyrazoles, dinucleophiles, rearrangement, Vilsmeier–Haack reagent.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv