METAL-CATALYZED SYNTHETIC STRATEGIES TOWARD COUMARIN DERIVATIVES

Authors

  • Rohit Bhatia Department of Pharmaceutical Chemistry, Indo-SovietFriendshipCollege of Pharmacy (ISFCP), Moga-142001 Research Scholar, Department of Pharmaceutical Sciences & Technology, MRSPTU, Bathinda-151001
  • Shelly Pathania Department of Pharmaceutical Chemistry, Indo-SovietFriendshipCollege of Pharmacy (ISFCP), Moga-142001 Research Scholar, Department of Pharmaceutical Sciences & Technology, MRSPTU, Bathinda-151001
  • Virender Singh Department of Chemistry and Biotechnology, Dr B R Ambedkar National Institute of Technology Jalandhar-144011, Punjab
  • Rawindra K. Rawal Department of Pharmaceutical Chemistry, Indo-SovietFriendshipCollege of Pharmacy (ISFCP), Moga-142001

DOI:

https://doi.org/10.1007/4517

Keywords:

coumarins, palladium, Knoevenagel condensation, metal catalysis, Pechmann condensation, synthetic routes.

Abstract

Modern approaches toward coumarin ring construction based on metal-catalyzed reactions significantly complement and extend the applicability of classical methods by increasing the reaction rates and product yields. The present review summarizes various approaches to the synthesis of coumarin derivatives catalyzed by different metals – palladium, gold, copper, silver, platinum, iron, cobalt, rhodium, gallium, nickel, and zinc. Among these, palladium-catalyzed reactions are the most numerous and significant in many aspects. The review covers literature over the last 20 years.

Downloads

Published

2018-05-15

Issue

Vol. 54 No. 3 (2018): Metal-catalyzed synthesis of heterocycles

Section

Review Articles