SYNTHESIS OF PYRIDONE-SUBSTITUTED FURAN-2(5 H )-ONES AND THEIR INTRAMOLECULAR CYCLIZATION TO AFFORD FURO[3,4- f ]ISOQUINOLINES

Robert M. Hakobyan; Sargis S. Hayotsyan; Hovhannes S. Attaryan; Gagik S. Melikyan

doi:10.1007/4587

SYNTHESIS OF PYRIDONE-SUBSTITUTED FURAN-2(5H)-ONES AND THEIR INTRAMOLECULAR CYCLIZATION TO AFFORD FURO[3,4-f]ISOQUINOLINES

Robert M. Hakobyan, Sargis S. Hayotsyan, Hovhannes S. Attaryan, Gagik S. Melikyan

Abstract

Synthetic approach toward pyridone-substituted furan-2(5H)-ones has been described. Intramolecular cyclization of these compounds leads to novel 7-substituted furo[3,4-f]isoquinolines in moderate to high yields.

Keywords

furan-2(5H)-one, furo[3,4-f]isoquinoline, pyridone, intramolecular cyclization

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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