STABILIZED AZOMETHINE YLIDES DERIVED FROM INDENO[1,2-b]QUINOXALINONES IN [3+2] CYCLOADDITION REACTIONS WITH ELECTROPHILIC ALKENES

Abstract

We provide a general and systematic review of all currently published data on the use of stabilized azomethine ylides derived from 11H-indeno[1,2-b]quinoxalin-11-one and 6H-indeno[1,2-b]pyrido[3,2-e]pyrazin-6-one in the synthesis of spiropyrrolidines and spiropyrrolizidines. The reaction conditions, as well as the regio- and stereoselectivity of the [3+2] cycloaddition process are discussed. Data on the biological activity of the obtained products are presented. There are 62 literature references.

Authors: Vladislav Yu. Korotaev, Nikolay S. Zimnitskiy, Alexey Yu. Barkov,
Igor B. Kutyashev, Vyacheslav Ya. Sosnovskikh