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SYNTHESIS AND STRUCTURE OF FUNCTIONALIZED PODANDS CONTAINING 4,7-DIHYDROTETRAZOLO[1,5-a]PYRIMIDINE RING. DIFFERENTLY SUBSTITUTED DIHYDROPYRIMIDINE PODANDS

Елена С. Филатова, Ольга В. Федорова, Павел А. Слепухин, Геннадий Л. Русинов, Валерий Н. Чарушин
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Abstract


The reaction of 3-oxobutanoate-containing polyethers with benzaldehyde and 5-aminotetrazole in the presence of polyphosphoric acid was used to synthesize podands containing two terminal tetrazolo[1,5-а]dihydropyrimidine groups. Byproducts were isolated and identified as podands containing different substituents – one 4,7-dihydrotetrazolo[1,5-а]pyrimidine ring system and a free hydroxy group at the other terminus of the polyether chain. Analogous differently substituted podands, including one 3,4-dihydropyrimidine-2(1H)-thione moiety, were isolated from the reactions of 3-oxobutanoate-containing polyethers with benzaldehyde and thiourea.

Authors: Elena S. Filatova*, Olga V. Fedorova, Pavel A. Slepukhin, Gennady L. Rusinov, Valery N. Charushin


Keywords


dihydropyrimidine thione podands; 4,7-dihydrotetrazolo[1,5-а]pyrimidine podands; differently substituted podands; transport polyether spacer; Biginelli reaction

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