DIASTEREOSELECTIVE SYNTHESIS OF 1,2,3-TRIAZOLINES FUSED WITH PENTANE AND DIHYDROPYRAN RINGS

Authors

  • Николай A. Беляев Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002
  • Татьяна B. Березкина Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002
  • Василий А. Бакулев Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002
  • Олег C. Ельцов Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002
  • Герт Любек Department of Neuroproteomics, Paracelsus Medical University, Salzburg 5020

DOI:

https://doi.org/10.1007/4740

Keywords:

azide, enamine, imidazole, triazine, triazoline

Abstract

As a result of studying the reactions of 5-azido-1-methyl-4-nitroimidazole and 2,4,5-trimethoxy-1,3,5-triazine with endocyclic enamines, a diastereoselective method was developed for the synthesis of 1-hetarylcycloalkano[1,2,3]triazolines with cis configuration of substituents at the bridgehead carbon atoms. The structures of the obtained reaction products were studied by methods of NMR spectroscopy, high-resolution mass spectrometry, and X-ray structural analysis.

Authors: Nikolay A. Belyaev, Tetyana V. Beryozkina, Vasiliy A. Bakulev*,
Oleg S. Eltsov, Gert Lubec

Author Biography

Василий А. Бакулев, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., Yekaterinburg 620002

Заведующий кафедрой Технологии органического синтеза

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Published

2018-11-09

Issue

Vol. 54 No. 10 (2018)

Section

Short Communications