

SYNTHESIS OF NOVEL SPIRO-CONDENSED 2-AMINO-4H-PYRANS BASED ON 1,2-BENZOXATHIIN-4(3H)-ONE 2,2-DIOXIDE

Abstract
A series of new spiro-condensed 2-amino-4H-pyrans were synthesized by three-component interaction of 1,2-benzoxathiin-4(3H)-one 2,2-dioxide, malononitrile, and cyclic carbonyls in moderate to high yields. This is one of the first examples of 1,2-benzoxathiin-4(3H)-one 2,2-dioxide application in multicomponent transformations.
Keywords
active methylene nitrile; 1,2-benzoxathiin-4(3H)-one 2,2-dioxide; isatin; ninhydrin; spiro compounds; multicomponent reactions
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv