SYNTHESIS OF 5-(5-AMINO-1 H -PYRAZOL-1-YL)- 1,2,3-THIADIAZOLE-4-CARBOXYLIC ACID ETHYL ESTERS AND THEIR CYCLIZATION INTO PYRAZOLO[1,5- a ][1,2,3]THIADIAZOLO[4,5- e ]PYRIMIDIN-4(5 H )-ONES

Ольга А. Высокова; Татьяна А. Калинина; Павел А. Слепухин; Татьяна А. Поспелова; Константин Л. Обыденнов; Татьяна В. Глухарева

doi:10.1007/4779

SYNTHESIS OF 5-(5-AMINO-1H-PYRAZOL-1-YL)- 1,2,3-THIADIAZOLE-4-CARBOXYLIC ACID ETHYL ESTERS AND THEIR CYCLIZATION INTO PYRAZOLO[1,5-a][1,2,3]THIADIAZOLO[4,5-e]PYRIMIDIN-4(5H)-ONES

Ольга А. Высокова, Татьяна А. Калинина, Павел А. Слепухин, Татьяна А. Поспелова, Константин Л. Обыденнов, Татьяна В. Глухарева

Abstract

A method for the synthesis of novel 1H-pyrazol-1-yl-1,2,3-thiadiazole derivatives has been proposed and their intramolecular cyclization to pyrazolo[1,5-a][1,2,3]thiadiazolo[4,5-e]pyrimidin-4(5H)-ones, previously unknown fused tricyclic heterocycles, has been studied.

Authors: Olga А. Vysokova, Tatiana A. Kalinina, Pavel А. Slepukhin,
Tatiana А. Pospelova, Konstantin L. Obydennov, Tatiana V. Glukhareva

Keywords

pyrazoles; pyrazolo[1,5-a]pyrimidines; pyrimidin-4(3H)-ones; 1,2,3-thiadiazoles; fused heterocycles; tricyclic heterocycles; condensation; X-ray structural analysis

Full Text: PDF (Russian) Open Access

Supplementary File(s): Supplementary Information (1MB)

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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