

SYNTHESIS OF N-SUBSTITUTED TETRAPROPARGYLAMINES BY CATALYTIC AMINOMETHYLATION OF Α,Ω-DIACETYLENES

Abstract
A catalytic method was developed for the synthesis of N-substituted tetrapropargylamines by reactions of α,ω-diacetylenes with 1,5,3-dioxazepanes, aldehydes (benzaldehydes, formaldehyde), and cyclic secondary amines.
Keywords
copper(I) chloride, α,ω-diacetylenes, 1,5,3-dioxazepanes, tetrapropargylamines, aminomethylation.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv