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EFFICIENT METHOD FOR THE SYNTHESIS OF 1,3-UNSUBSTITUTED 2-IMINO-5-OXOOCTAHYDROIMIDAZO[4,5-d]IMIDAZOLIUM IODIDES BASED ON THIOGLYCOLURILS

Vladimir V. Baranov, Evgeniya L. Yatsenko, Elizaveta K. Melnikova, Yulia V. Nelyubina, Angelina N. Kravchenko
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Abstract


A facile and efficient two-step synthetic route to previously inaccessible 1,3-unsubstituted 2-imino-5-oxooctahydroimidazo[4,5-d]imidazol-1-ium iodides has been developed using easily accessible thioglycolurils, MeI, and various primary amines, morpholine, or ethylene diamine. The structure of representative products and hydrogen-bonding pattern in their crystals have been investigated by X-ray diffraction.

Keywords


iminoglycolurils; isothiouronium salts; thioglycolurils; condensation; S-methylation

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