

EFFICIENT METHOD FOR THE SYNTHESIS OF 1,3-UNSUBSTITUTED 2-IMINO-5-OXOOCTAHYDROIMIDAZO[4,5-d]IMIDAZOLIUM IODIDES BASED ON THIOGLYCOLURILS

Abstract
A facile and efficient two-step synthetic route to previously inaccessible 1,3-unsubstituted 2-imino-5-oxooctahydroimidazo[4,5-d]imidazol-1-ium iodides has been developed using easily accessible thioglycolurils, MeI, and various primary amines, morpholine, or ethylene diamine. The structure of representative products and hydrogen-bonding pattern in their crystals have been investigated by X-ray diffraction.
Keywords
iminoglycolurils; isothiouronium salts; thioglycolurils; condensation; S-methylation
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv