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SYNTHESIS AND FUNGICIDAL ACTIVITY OF METHYLSULFANYLMETHYL ETHER DERIVATIVES OF LEVOGLUCOSENONE

Булат Т. Шарипов, Анна Н. Давыдова, Алена С. Рябова, Наиля Ф. Галимзянова, Фарид А. Валеев
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Abstract


A series of derivatives were synthesized on the basis of levoglucosenone that contained hydroxy groups at the С-4 atom or С-2 and С-4 atoms or a hydroxy and methyl group at the С-4 atom. In addition, 4-hydroxymethylbutanolides were synthesized. Derivatives containing hydroxy groups were obtained as methylsulfanylmethyl ethers. It was established that compounds containing a 6,8-dioxabicyclo[3.2.1]octane ring exhibited fungicidal activity against Rhizoctonia solani. It was shown that the presence of a methylsulfanylmethyl moiety in the ring could increase the fungicidal activity of compounds.

Authors: Bulat T. Sharipov*, Anna N. Davidova, Alena S. Ryabova, Nailya F. Galimzyanova, Farid A. Valeev


Keywords


γ-butanolides; levoglucosenone; methylthiomethyl ethers; fungicidal activity; Rhizoctonia solani

Full Text: PDF (Russian) Supplementary File(s): Supporting information (1MB)


 

 

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