TORP–ZIEGLER CYCLIZATION IN THE SYNTHESIS OF 3-AMINO-4-CYANOPYRROLE DERIVATIVES

C. А. Рындина, А. B. Кадушкин, Н. П. Соловьева, B. Г. Граник

Abstract


Polyfunctional derivatives of 3-aminopyrrole have been synthesized from several substituted β–enamino nitriles using Torp–Ziegler cyclization. These compounds are starting materials for further conversions, particularly for the synthesis of pyrrolo[3,2-d]- and pyrrolo[3,4-d]pyrimidines.

Authors: S. A. Ryndina, A. V. Kadushkin, N. P. Solov'eva, and V. G. Granik.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (12), pp 1409-1420

http://link.springer.com/article/10.1023/A%3A1017566212124


Keywords


3-amino-4-cyanopyrrole; β-enamino nitriles; pyrrolo[3,2-d]pyrimidines; pyrrolo[3,4-d]-pyrimidines; intramolecular cyclization; Torp–Ziegler cyclization

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