THE REACTION OF 4-AMINOCOUMARIN WITH β-CARBONYL-SUBSTITUTED 4<i>Н</i>-CHROMENES: SYNTHESIS OF 5<i>H</i>-CHROMENO[4,3-<i>b</i>]PYRIDIN-5-ONE DERIVATIVES
Authors
Дмитрий В. Осипов
Самарский государственный технический университет
Алина А. Артёменко
Самарский государственный технический университет
Виталий А. Осянин
Samara State Technical University
Юрий Н. Климочкин
Самарский государственный технический университет
4-aminocoumarin, chromene-3-carbaldehydes, 5H-chromeno[4, 3-b]pyridin-5-ones, Michael reaction
Abstract
Reactions of 4Н-chromene-3-carbaldehydes and 1Н-benzo[f]chromene-3-carbaldehydes with 4-aminocoumarin were used to obtain a series of pyridocoumarin derivatives containing a 2-hydroxybenzyl or 2-hydroxy-1-naphthyl substituent at the β-position relative to the nitrogen atom. The reaction mechanism includes a Michael reaction, chromane ring opening, and cyclodehydration.
