Open Access Open Access  Restricted Access Subscription Access

A NEW FACILE METHOD FOR THE SYNTHESIS OF 3-IMIDAZOLYLPROPIONIC ACID N-OXIDES

Anton V. Kutasevich, Valery P. Perevalov, Vitaly S. Mityanov, Boris V. Lichitsky, Andrey N. Komogortsev, Mikhail M. Krayushkin, Tatyana Yu. Koldaeva, Vladimir S. Miroshnikov
Cover Image

Abstract


A facile and efficient method for the preparation of 3-imidazolylpropionic acids N-oxides has been developed. It consists in the condensation of 2-unsubstituted imidazole N-oxide with aldehyde and Meldrum’s acid with the following hydrolysis of corresponding adduct. This method permits a broad variation in the structure of starting aldehydes as well as N-oxides.


Keywords


Russian Foundation for Basic Research

Full Text: PDF Supplementary File(s): supplementary info (7MB)


 

 

Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv