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ONE-POT THREE-COMPONENT SYNTHESIS OF POLYSUBSTITUTED TETRAHYDROINDOLES

Nataliia V. Chechina, Nadezhda N. Kolos, Irina V. Omelchenko
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Abstract


A series of novel fused pyrrole derivatives was synthesized by one-pot three-component reaction of β-enaminoketones, derived from cyclohexane-1,3-dione or dimedone, arylglyoxal hydrates, and 1,3-dimethylbarbituric acid in EtOH.

 




Keywords


β-alanine, arylglyoxal, cyclohexane-1,3-dione, dimedone, 1,3-dimethylbarbituric acid, β-enaminoketone, glycine, tetrahydroindole

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