ONE-POT THREE-COMPONENT SYNTHESIS OF POLYSUBSTITUTED TETRAHYDROINDOLES

Nataliia V. Chechina; Nadezhda N. Kolos; Irina V. Omelchenko

doi:10.1007/4908

ONE-POT THREE-COMPONENT SYNTHESIS OF POLYSUBSTITUTED TETRAHYDROINDOLES

Nataliia V. Chechina, Nadezhda N. Kolos, Irina V. Omelchenko

Abstract

A series of novel fused pyrrole derivatives was synthesized by one-pot three-component reaction of β-enaminoketones, derived from cyclohexane-1,3-dione or dimedone, arylglyoxal hydrates, and 1,3-dimethylbarbituric acid in EtOH.

Keywords

β-alanine, arylglyoxal, cyclohexane-1,3-dione, dimedone, 1,3-dimethylbarbituric acid, β-enaminoketone, glycine, tetrahydroindole

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv

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