

ONE-POT THREE-COMPONENT SYNTHESIS OF POLYSUBSTITUTED TETRAHYDROINDOLES

Abstract
A series of novel fused pyrrole derivatives was synthesized by one-pot three-component reaction of β-enaminoketones, derived from cyclohexane-1,3-dione or dimedone, arylglyoxal hydrates, and 1,3-dimethylbarbituric acid in EtOH.
Keywords
β-alanine, arylglyoxal, cyclohexane-1,3-dione, dimedone, 1,3-dimethylbarbituric acid, β-enaminoketone, glycine, tetrahydroindole
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv