ONE-POT THREE-COMPONENT SYNTHESIS OF POLYSUBSTITUTED TETRAHYDROINDOLES

Authors

  • Nataliia V. Chechina V. N. Karazin Kharkiv National University
  • Nadezhda N. Kolos V. N. Karazin Kharkiv National University
  • Irina V. Omelchenko V. N. Karazin Kharkiv National University, State Scientific Institution "Institute for Single Crystals", National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/4908

Keywords:

β-alanine, arylglyoxal, cyclohexane-1, 3-dione, dimedone, 1, 3-dimethylbarbituric acid, β-enaminoketone, glycine, tetrahydroindole

Abstract

A series of novel fused pyrrole derivatives was synthesized by one-pot three-component reaction of β-enaminoketones, derived from cyclohexane-1,3-dione or dimedone, arylglyoxal hydrates, and 1,3-dimethylbarbituric acid in EtOH.

 



Author Biographies

Nataliia V. Chechina, V. N. Karazin Kharkiv National University

asp.

Nadezhda N. Kolos, V. N. Karazin Kharkiv National University

prof.

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Published

2019-12-18

Issue

Vol. 55 No. 12 (2019)

Section

Original Papers