

N-BOC-4-AMINOPYRAZOLE-5-CARBALDEHYDES IN FRIENDLÄNDER SYNTHESIS OF PYRAZOLO[4,3-b]PYRIDINES

Abstract
N-Boc-4-aminopyrazole-5-carbaldehydes reacted with aryl, hetaryl, alkyl, and cycloalkyl ketones containing methylene groups. The reactions were accomplished in refluxing acetic acid in the presence of pyrrolidine and resulted in the formation of 5-substituted and carbo[b]fused pyrazolo[4,3-b]pyridines.
Authors: Georgiy G. Yakovenko*, Oleh A. Lukianov, Andriy V. Bol'but, Mykhailo V. Vovk
Keywords
4-аминопиразол-5-карбальдегиды; кетоны; пиразоло[4,3-b]пиридины; реакция Фридлендера
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv