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SYNTHESIS OF CHROMENO[2,3-c]PYRROL-9(2H)-ONES BY DOMINO REACTIONS OF AMINO ACIDS WITH YNONES

Mariia Miliutina, Yevhen Ivon, Evgeniy Y. Slobodyanyuk, Syeda Abida Ejaz, Jamshed Iqbal, Alexander Villinger, Viktor O. Iaroshenko, Peter Langer
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Abstract


The synthesis of novel chromeno[2,3-c]pyrrol-9(2H)-ones via domino reaction of amino acids with aromatic α,β-ynones is described. Obtained chromeno[2,3-c]pyrrol-9(2H)-ones possess phosphatase inhibitory activity.

 


Keywords


amino acids, chromeno[2,3-c]pyrrol-9(2H)-ones, heterocycles, alkaline phosphatase inhibitory activity, domino reactions.

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