

SYNTHESIS OF 7-ARYLIMIDAZO[1,2-a]PYRAZIN-8(7H)-ONE DERIVATIVES

Abstract
A suitable approach to the synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-ones starting from esters of oxalic acid monoamides via cyclization of intermediate 3-aminopyrazin-2-ones with α-halocarbonyl compounds has been suggested.
Keywords
3-aminopyrazin-2(1H)-one; 2-halophenylethanone; imidazo[1,2-a]pyrazin-8(7H)-one; 3-methoxypyrazin-2(1H)-one; pyrazine-2,3-dione; cyclization
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv