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SYNTHESIS OF 7-ARYLIMIDAZO[1,2-a]PYRAZIN-8(7H)-ONE DERIVATIVES

Svitlana S. Kovalenko, Oleksandr G. Drushlyak, Sergiy M. Kovalenko, Natalya D. Bunyatyan, Dmitry V. Kravchenko, Alexandre V. Ivachtchenko
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Abstract


A suitable approach to the synthesis of 7-arylimidazo[1,2-a]pyrazin-8(7H)-ones starting from esters of oxalic acid monoamides via cyclization of intermediate 3-aminopyrazin-2-ones with α-halocarbonyl compounds has been suggested.

Keywords


3-aminopyrazin-2(1H)-one; 2-halophenylethanone; imidazo[1,2-a]pyrazin-8(7H)-one; 3-methoxypyrazin-2(1H)-one; pyrazine-2,3-dione; cyclization

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