

REACTIONS OF N-SULFONYL-1,2,3-THIADIAZOLE-4-CARBIMIDAMIDES WITH SULFONYL CHLORIDES: REGIOSPECIFIC SYNTHESIS AND STRUCTURE OF 2-SULFONYL-1,2,3-TRIAZOLES

Abstract
Sulfonylation of 1,2,3-thiadiazolecarboxylic acid amidines in the presence of a base was found to be accompanied by the Cornforth rearrangement of the 1,2,3-thiadiazole ring into 1,2,3-triazole leading to the formation of 2-substituted 1,2,3-triazoles in high yields.
Keywords
N-sulfonyl amidines, 2-sulfonyl-1,2,3-triazoles, sulfonyl chlorides, 1,2,3-thiadiazoles, rearrangement.
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv