CONJUGATED 2,4,1- AND 1,4,3-ENYNONES AS POLYCENTRIC ELECTROPHILES IN SYNTHESIS OF HETEROCYCLIC COMPOUNDS

Authors

  • Александр А. Голованов Togliatti State University, 14 Belorusskaya St., Togliatti 445020
  • Дмитрий М. Гусев Togliatti State University, 14 Belorusskaya St., Togliatti 445020
  • Иван С. Один Togliatti State University, 14 Belorusskaya St., Togliatti 445020
  • Семен C. Злотский Ufa State Petroleum Technological University, 1 Kosmonavtov St., Ufa 450062

DOI:

https://doi.org/10.1007/4985

Keywords:

aziridines, conjugated enynones, furans, pyrazoles, pyrimidines, 1, 2, 3-triazoles, biological activity, cyclization, 3-dipolar cycloaddition, nucleophilic addition

Abstract

This review article provides critical analysis of literature data regarding the heterocyclization reactions of compounds containing alk-2-en-4-yn-1-one and alk-1-en-4-yn-3-one moieties. We discuss the reactions leading to the formation of furans, 2,3-dihydropyrans, 1,2,3-triazoles, 4,5-dihydro-1Н-pyrazoles, pyrazoles, isoxazoles, pyrimidines, aziridines, as well as a range of more complex fused ring systems. The biological activity and photophysical properties of the obtained heterocyclic compounds are described. The attention is mainly focused on the studies published during the last 5 years. A total of 87 references are given.

Authors: Alexander A. Golovanov*, Dmitry M. Gusev,
Ivan S. Odin, Simon S. Zlotskii

Author Biography

Александр А. Голованов, Togliatti State University, 14 Belorusskaya St., Togliatti 445020

Александр Александрович Голованов

Department of Chemistry and Chemical Technology, docent

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Published

2019-05-22

Issue

Vol. 55 No. 4/5 (2019): In memory of Professor Valerii Dmitrievich Orlov

Section

Review Articles