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AN EFFICIENT SYNTHESIS OF NOVEL 11H-CHROMENO[3',2':3,4]PYRROLO[2,1-b][1,3]THIAZOL-11-ONE HETEROCYCLIC SYSTEM

Tetiana V. Shokol, Natalia V. Gorbulenko, Volodymir P. Khilya
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Abstract


An effective approach to the synthesis of the first examples of novel ring systems 11H-chromeno[3',2':3,4]pyrrolo[2,1-b][1,3]thiazol-11-one and 13H-chromeno[3',2':3.4]pyrrolo[2,1-b][1,3]benzothiazol-13-one via intramolecular cyclization of 3-[1,3-(benzo)thiazol-2-yl]-2-chloromethylchromones has been developed.

 


Keywords


13H-chromeno[3',2':3.4]pyrrolo[2,1-b][1,3]benzothiazol-13-one, 3-[1,3-(benzo)thiazol-2-yl]-2-chloromethyl-7-hydroxy-4Н-chromen-4-оnes, 11H-chromeno[3',2':3,4]pyrrolo[2,1-b][1,3]thiazol-11-ones, condensed chromones, heterocyclization.

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Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv