

SYNTHESIS OF ANABASINE-CONTAINING AMINOMETHYL DERIVATIVES OF 6-HYDROXYAURONES

Abstract
Aminomethylation of aurones was studied by using anabasine. The reaction in the case of 6-hydroxyaurones was shown to selectively provide 7-aminomethyl-6-hydroxyaurones, while 5-aminomethyl-6-hydroxy-7-methylaurones could be obtained by transamination of 5-dimethylaminomethyl derivatives of 6-hydroxy-7-methylaurones in the presence of anabasine.
Keywords
anabasine; benzofuran-3(2Н)-one; 6-hydroxyaurone; aminomethylation; Mannich base
Latvian Institute of Organic Synthesis - Aizkraukles iela, 21, Riga, LV-1006, Latvia - hgs@osi.lv