SYNTHESIS OF 2-AMINO-6-(NITROIMIDAZOLYL)THIOPURINES

Authors

  • П. М. Кочергин Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow
  • E. В. Александрова Zaporozhye State Medical University
  • B. C. Корсунский Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow
  • B. C. Шлихунова Drug Chemistry Center, All-Russian Pharmaceutical Chemistry Scientific Research Institute, Moscow

DOI:

https://doi.org/10.1007/50

Keywords:

halonitroimidazoles, nitroimidazolylthioguanines, thioguanine, immunodepressants

Abstract

We have synthesized a series of novel 2-amino-6-(nitroimidazolyl)thiopurines by reaction of thioguanine with 1-alkyl(1,2-dialkyl)-5-chloro-4-nitro-, 2-alkyl(1,2-dialkyl)-5-bromo-4-nitro-, and 1-alkyl(1,2-dialkyl)-4-chloro-5-nitroimidazoles.

Authors: P. M. Kochergin, E. V. Aleksandrova, V. S. Korsunskii, and V. S. Shlikhunova.

English Translation in Chemistry of Heterocyclic Compounds, 2000, 36 (2), pp 182-184

http://link.springer.com/article/10.1007/BF02283549

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Published

2012-11-16

Issue

No. 2 (2000)

Section

Original Papers