INVESTIGATIONS ON FUROPYRIDINES. 10. SYNTHESIS OF 4-N-SUBSTITUTED 1H-FURO[3,4-<i>c</i>]PYRIDIN-3-ONES

Abstract

2-Amino or 2-hydrazino derivatives of pyridine or pyridinopyrazole were obtained by amination or hydrazination of 2-chloro-3-cyano-4-methoxy-6-methylpyridine. Acid hydrolysis of these derivatives leads to heterocyclization with formation of 4-amino-1H-furo[3,4-c]pyridines or pyrazolo[3,4-b]pyridine. The possibility to synthesize 4-arylamino-1H-furo[3,4-c]-pyridines from 4-chloro-6-methyl-1H-furo[3,4-c]-pyridine has been shown.

Authors: I. S. Arustamova and V. T. Piven'.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (1), pp 58-63

http://link.springer.com/article/10.1007/BF02251662